Cd47 Ligation Selectively Downregulates Human Interleukin 12 Production

Interleukin (IL)-12 plays a key role not only in protective innate and adaptive T helper cell type 1 (Th1) responses but also in chronic inflammatory diseases. We report here that engagement of CD47 by either monoclonal antibody, its natural ligand thrombospondin (TSP), or 4N1K (a peptide of the COO...

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Detalles Bibliográficos
Autores principales: Armant, Myriam, Avice, Marie-Noëlle, Hermann, Patrice, Rubio, Manuel, Kiniwa, Mamoru, Delespesse, Guy, Sarfati, Marika
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1999
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195669/
https://ncbi.nlm.nih.gov/pubmed/10523615
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