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Protective T Cell–Independent Antiviral Antibody Responses Are Dependent on Complement

Complement is part of the innate immune system and one of the first lines of host defense against infections. Its importance was evaluated in this study in virus infections in mice deficient either in soluble complement factors (C3(−/−), C4(−/−)) or in the complement signaling complex (complement re...

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Autori principali: Ochsenbein, Adrian F., Pinschewer, Daniel D., Odermatt, Bernhard, Carroll, Michael C., Hengartner, Hans, Zinkernagel, Rolf M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195668/
https://ncbi.nlm.nih.gov/pubmed/10523614
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