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Human Dendritic Cells Mediate Cellular Apoptosis via Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail)

TRAIL (TNF-related apoptosis-inducing ligand) is a member of the TNF family that induces apoptosis in a variety of cancer cells. In this study, we demonstrate that human CD11c(+) blood dendritic cells (DCs) express TRAIL after stimulation with either interferon (IFN)-γ or -α and acquire the ability...

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Bibliographic Details
Main Authors: Fanger, Neil A., Maliszewski, Charles R., Schooley, Ken, Griffith, Thomas S.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195665/
https://ncbi.nlm.nih.gov/pubmed/10523613
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