Pim1 Reconstitutes Thymus Cellularity in Interleukin 7–And Common γ Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not Cd3γ-Deficient Mice

The majority of lymphomas induced in Rag-deficient mice by Moloney murine leukemia virus (MoMuLV) infection express the CD4 and/or CD8 markers, indicating that proviral insertions cause activation of genes affecting the development from CD4(−)8(−) pro-T cells into CD4(+)8(+) pre-T cells. Similar to...

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Bibliografiska uppgifter
Huvudupphovsmän: Jacobs, Heinz, Krimpenfort, Paul, Haks, Mariëlle, Allen, John, Blom, Bianca, Démollière, Corinne, Kruisbeek, Ada, Spits, Hergen, Berns, Anton
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 1999
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195657/
https://ncbi.nlm.nih.gov/pubmed/10523604
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