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Endothelial Cells Modify the Costimulatory Capacity of Transmigrating Leukocytes and Promote Cd28-Mediated Cd4(+) T Cell Alloactivation

Activated vascular endothelial cells (ECs) express major histocompatibility complex (MHC) class II molecules in vitro and in vivo in acute and chronic allograft rejection. However, human ECs may be limited in their ability to effectively activate CD4(+) T cells, because they do not express members o...

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Bibliografiske detaljer
Main Authors: Denton, Mark D., Geehan, Christopher S., Alexander, Steve I., Sayegh, Mohamed H., Briscoe, David M.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195607/
https://ncbi.nlm.nih.gov/pubmed/10449526
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