Novel Point Mutation in the Extracellular Domain of the Granulocyte Colony-Stimulating Factor (G-Csf) Receptor in a Case of Severe Congenital Neutropenia Hyporesponsive to G-Csf Treatment

Severe congenital neutropenia (SCN) is a heterogeneous condition characterized by a drastic reduction in circulating neutrophils and a maturation arrest of myeloid progenitor cells in the bone marrow. Usually this condition can be successfully treated with granulocyte colony-stimulating factor (G-CS...

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Main Authors: Ward, Alister C., van Aesch, Yvette M., Gits, Judith, Schelen, Anita M., de Koning, John P., van Leeuwen, Daphne, Freedman, Melvin H., Touw, Ivo P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195597/
https://ncbi.nlm.nih.gov/pubmed/10449521
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