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Mice Deficient in Nuclear Factor of Activated T-Cell Transcription Factor c2 Mount Increased Th2 Responses after Infection with Nippostrongylus brasiliensis and Decreased Th1 Responses after Mycobacterial Infection

Infection of nuclear factor of activated T-cell transcription factor c2 (NFATc2)-deficient mice with the helminth Nippostrongylus brasiliensis led to a distinct increase in interleukin-4 (IL-4) and IL-5 protein synthesis by lymph node and spleen cells and to elevated serum immunoglobulin E (IgE) lev...

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Main Authors: Erb, Klaus J., Twardzik, Thomas, Palmetshofer, Alois, Wohlleben, Gisela, Tatsch, Ursula, Serfling, Edgar
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC219542/
https://ncbi.nlm.nih.gov/pubmed/14573689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.11.6641-6647.2003
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