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JNK/c-Jun signaling pathway mediates the fluoride-induced down-regulation of MMP-20 in vitro

Delayed removal of amelogenins, which are initially hydrolyzed by matrix metalloproteinase MMP-20, is a characteristic of enamel fluorosis. In this study, we investigated the regulation of MMP-20 and possible effects of fluoride on MMP-20 expression in human ameloblast lineage cells. Protein express...

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Hlavní autoři: Zhang, Yan, Li, Wu, Chi, Hae Sun, Chen, James, DenBesten, Pamela K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194802/
https://ncbi.nlm.nih.gov/pubmed/17611094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2007.06.002
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