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Improved human disease candidate gene prioritization using mouse phenotype

BACKGROUND: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-throughput genome-wide studies like linkage analysis and gene expression profiling, tend to be most useful for classification...

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書目詳細資料
Main Authors: Chen, Jing, Xu, Huan, Aronow, Bruce J, Jegga, Anil G
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194797/
https://ncbi.nlm.nih.gov/pubmed/17939863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-392
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