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Hexameric RSF1010 helicase RepA: the structural and functional importance of single amino acid residues

In the known monoclinic crystals the 3-dimensional structure of the hexameric, replicative helicase RepA encoded by plasmid RSF1010 shows 6-fold rotational symmetry. In contrast, in the cubic crystal form at 2.55 Å resolution described here RepA has 3-fold symmetry and consists of a trimer of dimers...

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Bibliographic Details
Main Authors: Ziegelin, Günter, Niedenzu, Timo, Lurz, Rudi, Saenger, Wolfram, Lanka, Erich
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC219471/
https://ncbi.nlm.nih.gov/pubmed/14530440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg790
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