The inflammation-induced down-regulation of plasma Fetuin-A (α2HS-Glycoprotein) in liver results from the loss of interaction between long C/EBP isoforms at two neighbouring binding sites

Fetuin-A is an hepatic protein whose mRNA transiently falls during the inflammatory acute phase via unknown transcriptional mechanisms. Various FETUA promoter/cat constructs transiently transfected in the Hep3B hepatoma cell line allowed us to identify four NF-1 and C/EBP binding sites (N, C) arrang...

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Autori principali: Gangneux, Christophe, Daveau, Maryvonne, Hiron, Martine, Derambure, Céline, Papaconstantinou, John, Salier, Jean-Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2003
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC219469/
https://ncbi.nlm.nih.gov/pubmed/14530444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg788
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