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Tamoxifen Neuroprotection in Cerebral Ischemia Involves Attenuation of Kinase Activation and Superoxide Production and Potentiation of Mitochondrial Superoxide Dismutase

The purpose of this study was to enhance our understanding of the mechanisms of neuronal death after focal cerebral ischemia and the neuroprotective effects of tamoxifen (TMX). The phosphorylation state of 31 protein kinases/signaling proteins and superoxide anion (O(2)(−)) production in the contral...

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書誌詳細
主要な著者: Wakade, Chandramohan, Khan, Mohammad M., De Sevilla, Liesl M., Zhang, Quan-Guang, Mahesh, Virendra B., Brann, Darrell W.
フォーマット: Artigo
言語:Inglês
出版事項: The Endocrine Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194601/
https://ncbi.nlm.nih.gov/pubmed/17901229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0899
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