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Mechanisms accelerating muscle atrophy in catabolic diseases.
In summary, muscle protein loss in uremia is related to activation of the ubiquitin-proteasome proteolytic system to degrade muscle proteins. This response invariably includes increased transcription of genes encoding components of this pathway, suggesting that these illnesses stimulate a program of...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Clinical and Climatological Association
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194388/ https://ncbi.nlm.nih.gov/pubmed/10881345 |
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