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Down-regulation of CD46 by Piliated Neisseria gonorrhoeae

Human membrane cofactor protein (CD46) protects host cells against complement attack and may function as a receptor for pathogenic Neisseriae. We assessed CD46 expression in the human cervical cell line ME-180 after exposure to Neisseria gonorrhoeae. Piliated but not nonpiliated gonococci adhered to...

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Main Authors: Gill, Darcy B., Koomey, Michael, Cannon, Janne G., Atkinson, John P.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194255/
https://ncbi.nlm.nih.gov/pubmed/14597734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031159
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