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Intracellular Recognition of Lipopolysaccharide by Toll-like Receptor 4 in Intestinal Epithelial Cells

Toll-like receptor (TLR)4 has recently been shown to reside in the Golgi apparatus of intestinal crypt epithelial m-IC(cl2) cells, colocalizing with internalized lipopolysaccharide (LPS). Here we demonstrate that disruption of the integrity of the Golgi apparatus significantly reduced LPS-mediated n...

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Detalhes bibliográficos
Main Authors: Hornef, Mathias W., Normark, Birgitta Henriques, Vandewalle, Alain, Normark, Staffan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194240/
https://ncbi.nlm.nih.gov/pubmed/14568981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20022194
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