Plasmin Activates the Lymphangiogenic Growth Factors VEGF-C and VEGF-D

Vascular endothelial growth factor (VEGF) C and VEGF-D stimulate lymphangiogenesis and angiogenesis in tissues and tumors by activating the endothelial cell surface receptor tyrosine kinases VEGF receptor (VEGFR) 2 and VEGFR-3. These growth factors are secreted as full-length inactive forms consisti...

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Detalhes bibliográficos
Main Authors: McColl, Bradley K., Baldwin, Megan E., Roufail, Sally, Freeman, Craig, Moritz, Robert L., Simpson, Richard J., Alitalo, Kari, Stacker, Steven A., Achen, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194198/
https://ncbi.nlm.nih.gov/pubmed/12963694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030361
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