CD226 (DNAM-1) Is Involved in Lymphocyte Function–associated Antigen 1 Costimulatory Signal for Naive T Cell Differentiation and Proliferation

Upon antigen recognition by the T cell receptor, lymphocyte function–associated antigen 1 (LFA-1) physically associates with the leukocyte adhesion molecule CD226 (DNAM-1) and the protein tyrosine kinase Fyn. We show that lentiviral vector-mediated mutant (Y-F(322)) CD226 transferred into naive CD4(...

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Hauptverfasser: Shibuya, Kazuko, Shirakawa, Jun, Kameyama, Tomie, Honda, Shin-ichiro, Tahara-Hanaoka, Satoko, Miyamoto, Akitomo, Onodera, Masafumi, Sumida, Takayuki, Nakauchi, Hiromitsu, Miyoshi, Hiroyuki, Shibuya, Akira
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2003
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194159/
https://ncbi.nlm.nih.gov/pubmed/14676297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030958
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