The Neurotrophins Nerve Growth Factor, Brain-derived Neurotrophic Factor, Neurotrophin-3, and Neurotrophin-4 Are Survival and Activation Factors for Eosinophils in Patients with Allergic Bronchial Asthma

Neurotrophins (nerve growth factor [NGF], brain-derived neurotrophic factor [BDNF], neurotrophin [NT]-3, and NT-4) have been observed in elevated concentrations in allergic diseases. Neurotrophin levels are up-regulated endobronchially after allergen challenge. This coincides with an influx of activ...

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Main Authors: Nassenstein, Christina, Braun, Armin, Erpenbeck, Veit Johannes, Lommatzsch, Marek, Schmidt, Stephanie, Krug, Norbert, Luttmann, Werner, Renz, Harald, Virchow, Johann Christian
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2003
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194097/
https://ncbi.nlm.nih.gov/pubmed/12900521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20010897
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