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A Conduit System Distributes Chemokines and Small Blood-borne Molecules through the Splenic White Pulp

Access to the splenic white pulp is restricted to lymphocytes and dendritic cells. Here we show that movement of molecules from the blood into these confined areas is also limited. Large molecules, such as bovine serum albumin (68 kD), immunoglobulin G (150 kD), and 500 kD dextran are unable to ente...

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Autors principals: Nolte, Martijn A., Beliën, Jeroen A.M., Schadee-Eestermans, Inge, Jansen, Wendy, Unger, Wendy W.J., van Rooijen, Nico, Kraal, Georg, Mebius, Reina E.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194088/
https://ncbi.nlm.nih.gov/pubmed/12900524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021801
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