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Toll-like Receptor 9–mediated Recognition of Herpes Simplex Virus-2 by Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) have been identified as a potent secretor of the type I interferons (IFNs) in response to CpG as well as several viruses. In this study, we examined the molecular mechanism of virus recognition by pDCs. First, we demonstrated that the CD11c(+)Gr-1(int)B220(+) pDCs...

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Autori principali: Lund, Jennifer, Sato, Ayuko, Akira, Shizuo, Medzhitov, Ruslan, Iwasaki, Akiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194085/
https://ncbi.nlm.nih.gov/pubmed/12900525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030162
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