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Vaccination with Minigenes Encoding V(H)-derived Major Histocompatibility Complex Class I–binding Epitopes Activates Cytotoxic T Cells that Ablate Autoantibody-producing B Cells and Inhibit Lupus
Current treatments for autoantibody-mediated diseases, such as lupus, can cause nonspecific immune suppression. In this paper, we used a bioinformatic approach to identify major histocompatibility complex class I–binding epitopes in the heavy chain variable region of anti-DNA antibodies from lupus-p...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194049/ https://ncbi.nlm.nih.gov/pubmed/12235207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020223 |
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