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Identification of the Lateral Interaction Surfaces of Human Histocompatibility Leukocyte Antigen (HLA)-DM with HLA-DR1 by Formation of Tethered Complexes That Present Enhanced HLA-DM Catalysis

Human histocompatibility leukocyte antigen (HLA)-DM is a major histocompatibility complex (MHC)-like protein that catalyzes exchange of antigenic peptides from MHC class II molecules. To investigate the molecular details of this catalysis we created four covalent complexes between HLA-DM and the MHC...

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Autors principals: Stratikos, Efstratios, Mosyak, Lidia, Zaller, Dennis M., Wiley, Don C.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193930/
https://ncbi.nlm.nih.gov/pubmed/12119342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020117
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