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Delayed Cellular Maturation and Decreased Immunoglobulin κ Light Chain Production In Immature B Lymphocytes Lacking B Cell Linker Protein
B cell linker (BLNK) protein is a component of the B cell receptor (BCR) signaling pathway and BLNK(−/−) mice have a block in B lymphopoiesis at the pro-B/pre-B cell stage. To study the effect of BLNK mutation at later stages of B cell development, we introduce an innocuous transgenic BCR into BLNK(...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193924/ https://ncbi.nlm.nih.gov/pubmed/12119344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020172 |
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