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Effect of Anatomical Distribution of Mast Cells on Their Defense Function against Bacterial Infections: Demonstration Using Partially Mast Cell–deficient tg/tg Mice

Mast cells were depleted in the peritoneal cavity of WBB6F(1)-tg/tg mice that did not express a transcription factor, MITF. When acute bacterial peritonitis was induced in WBB6F(1)-+/+, WBB6F(1)-W/W (v), and WBB6F(1)-tg/tg mice, the proportion of surviving WBB6F(1)-+/+ mice was significantly higher...

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Detalhes bibliográficos
Main Authors: Jippo, Tomoko, Morii, Eiichi, Ito, Akihiko, Kitamura, Yukihiko
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193916/
https://ncbi.nlm.nih.gov/pubmed/12771178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20022157
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