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Protein Kinase C θ Affects Ca(2+) Mobilization and NFAT Activation in Primary Mouse T Cells
Protein kinase C (PKC)θ is an established component of the immunological synapse and has been implicated in the control of AP-1 and NF-κB. To study the physiological function of PKCθ, we used gene targeting to generate a PKCθ null allele in mice. Consistently, interleukin 2 production and T cell pro...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193906/ https://ncbi.nlm.nih.gov/pubmed/12782715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020234 |
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