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A Role of Suppressor of Cytokine Signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated Interleukin 2 Production

Suppressor of cytokine signaling (SOCS)3 has been characterized as a negative feedback regulator in cytokine-mediated Janus kinase signal transducer and activator of transcription signaling. However, this study shows that T cells from transgenic mice expressing SOCS3 exhibit a significant reduction...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matsumoto, Akira, Seki, Yoh-ichi, Watanabe, Ryosuke, Hayashi, Katsuhiko, Johnston, James A., Harada, Yohsuke, Abe, Ryo, Yoshimura, Akihiko, Kubo, Masato
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193868/
https://ncbi.nlm.nih.gov/pubmed/12591901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020939
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