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Description and Interpretation of Adaptive Evolution of Escherichia coli K-12 MG1655 by Using a Genome-Scale In Silico Metabolic Model

Genome-scale in silico metabolic networks of Escherichia coli have been reconstructed. By using a constraint-based in silico model of a reconstructed network, the range of phenotypes exhibited by E. coli under different growth conditions can be computed, and optimal growth phenotypes can be predicte...

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Autori principali: Fong, Stephen S., Marciniak, Jennifer Y., Palsson, Bernhard Ø.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC219384/
https://ncbi.nlm.nih.gov/pubmed/14563875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.21.6400-6408.2003
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