Activation of Dendritic Cells through the Interleukin 1 Receptor 1 Is Critical for the Induction of Autoimmune Myocarditis

Dilated cardiomyopathy, resulting from myocarditis, is the most common cause of heart failure in young patients. We here show that interleukin (IL)-1 receptor type 1–deficient (IL-1R1(−/−)) mice are protected from development of autoimmune myocarditis after immunization with α-myosin-peptide(614–629...

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Hauptverfasser: Eriksson, Urs, Kurrer, Michael O., Sonderegger, Ivo, Iezzi, Giandomenica, Tafuri, Anna, Hunziker, Lukas, Suzuki, Shinobu, Bachmaier, Kurt, Bingisser, Roland M., Penninger, Josef M., Kopf, Manfred
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2003
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193833/
https://ncbi.nlm.nih.gov/pubmed/12566416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021788
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