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Disruption of Transforming Growth Factor β Signaling by a Novel Ligand-dependent Mechanism

Transforming growth factor (TGF)-β is the prototype in a family of secreted proteins that act in autocrine and paracrine pathways to regulate cell development and function. Normal cells typically coexpress TGF-β receptors and one or more isoforms of TGF-β, thus the synthesis and secretion of TGF-β a...

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Autori principali: Fernandez, Tania, Amoroso, Stephanie, Sharpe, Shellyann, Jones, Gary M., Bliskovski, Valery, Kovalchuk, Alexander, Wakefield, Lalage M., Kim, Seong-Jin, Potter, Michael, Letterio, John J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193757/
https://ncbi.nlm.nih.gov/pubmed/12021305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011521
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