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CD8 T Cells Are Required for the Formation of Ectopic Germinal Centers in Rheumatoid Synovitis

The assembly of inflammatory lesions in rheumatoid arthritis is highly regulated and typically leads to the formation of lymphoid follicles with germinal center (GC) reactions. We used microdissection of such extranodal follicles to analyze the colonizing T cells. Although the repertoire of follicul...

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Autores principales: Kang, Young Mo, Zhang, Xiaoyu, Wagner, Ulf G., Yang, Hongyu, Beckenbaugh, Robert D., Kurtin, Paul J., Goronzy, Jörg J., Weyand, Cornelia M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193749/
https://ncbi.nlm.nih.gov/pubmed/12021312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011565
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