Cbl Associates with Pyk2 and Src to Regulate Src Kinase Activity, α(v)β(3) Integrin-Mediated Signaling, Cell Adhesion, and Osteoclast Motility

The signaling events downstream of integrins that regulate cell attachment and motility are only partially understood. Using osteoclasts and transfected 293 cells, we find that a molecular complex comprising Src, Pyk2, and Cbl functions to regulate cell adhesion and motility. The activation of integ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sanjay, Archana, Houghton, Adam, Neff, Lynn, DiDomenico, Emilia, Bardelay, Chantal, Antoine, Evelyne, Levy, Joan, Gailit, James, Bowtell, David, Horne, William C., Baron, Roland
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2001
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193648/
https://ncbi.nlm.nih.gov/pubmed/11149930
Tagiau: Ychwanegu Tag
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