Cbl Associates with Pyk2 and Src to Regulate Src Kinase Activity, α(v)β(3) Integrin-Mediated Signaling, Cell Adhesion, and Osteoclast Motility

The signaling events downstream of integrins that regulate cell attachment and motility are only partially understood. Using osteoclasts and transfected 293 cells, we find that a molecular complex comprising Src, Pyk2, and Cbl functions to regulate cell adhesion and motility. The activation of integ...

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Hlavní autoři: Sanjay, Archana, Houghton, Adam, Neff, Lynn, DiDomenico, Emilia, Bardelay, Chantal, Antoine, Evelyne, Levy, Joan, Gailit, James, Bowtell, David, Horne, William C., Baron, Roland
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2001
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193648/
https://ncbi.nlm.nih.gov/pubmed/11149930
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