Biosynthesis of Glycosylphosphatidylinositol Is Essential to the Survival of the Protozoan Parasite Toxoplasma gondii

The PIGA gene from Toxoplasma gondii has been cloned and characterized. Like mammalian PIGA, the transmembrane and C-terminal domains are sufficient to direct localization to the parasite endoplasmic reticulum. A functional copy of PIGA is required for tachyzoite viability, demonstrating that glycos...

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Argitaratua izan da:	Eukaryot Cell
Egile Nagusiak:	Wichroski, Michael J., Ward, Gary E.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2003
Gaiak:	Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC219362/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14555496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/EC.2.5.1132-1136.2003
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