Sialylated O-Glycans and Sulfated Tyrosines in the NH(2)-Terminal Domain of CC Chemokine Receptor 5 Contribute to High Affinity Binding of Chemokines

The chemokine receptor CCR5 plays an important role in leukocyte chemotaxis and activation, and also acts as a coreceptor for human and simian immunodeficiency viruses (HIV-1, HIV-2, and SIV). We provide evidence that CCR5 is O-glycosylated on serine 6 in the NH(2) terminus. The O-linked glycans, pa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bannert, Norbert, Craig, Stewart, Farzan, Michael, Sogah, Dodzie, Santo, Niki Villanueva, Choe, Hyeryun, Sodroski, Joseph
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2001
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193526/
https://ncbi.nlm.nih.gov/pubmed/11733580
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak