Cytokines Regulate Proteolysis in Major Histocompatibility Complex Class II–Dependent Antigen Presentation by Dendritic Cells

Endo/lysosomal proteases control two key events in antigen (Ag) presentation: the degradation of protein Ag and the generation of peptide-receptive major histocompatibility complex (MHC) class II molecules. Here we show that the proinflammatory cytokines tumor necrosis factor α and interleukin (IL)-...

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Autores principales: Fiebiger, Edda, Meraner, Paul, Weber, Ekkehard, Fang, I-Fei, Stingl, Georg, Ploegh, Hidde, Maurer, Dieter
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2001
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193402/
https://ncbi.nlm.nih.gov/pubmed/11304549
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