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Lyn Is Essential for Fcγ Receptor III–Mediated Systemic Anaphylaxis but Not for the Arthus Reaction

The Src family kinase Lyn initiates intracellular signal transduction by associating with a variety of immune receptors such as antigen receptor on B cells and high-affinity Fc receptor (FcR) for immunoglobulin Ig(E) (FcεRI) on mast cells. Involvement of Lyn in the IgE-mediated immediate-type hypers...

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Bibliographic Details
Main Authors: Yuasa, Takae, Ono, Masao, Watanabe, Takeshi, Takai, Toshiyuki
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193394/
https://ncbi.nlm.nih.gov/pubmed/11238587
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