Treatment of Allergic Airway Inflammation and Hyperresponsiveness by Antisense-Induced Local Blockade of Gata-3 Expression

Recent studies in transgenic mice have revealed that expression of a dominant negative form of the transcription factor GATA-3 in T cells can prevent T helper cell type 2 (Th2)-mediated allergic airway inflammation in mice. However, it remains unclear whether GATA-3 plays a role in the effector phas...

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Detalhes bibliográficos
Main Authors: Finotto, Susetta, De Sanctis, George T., Lehr, Hans A., Herz, Udo, Buerke, Michael, Schipp, Mechthild, Bartsch, Brigitte, Atreya, Raja, Schmitt, Edgar, Galle, Peter R., Renz, Harald, Neurath, Markus F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193377/
https://ncbi.nlm.nih.gov/pubmed/11390432
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