A NASP (N1/N2)-Related Protein, Sim3, Binds CENP-A and Is Required for Its Deposition at Fission Yeast Centromeres

A defining feature of centromeres is the presence of the histone H3 variant CENP-A(Cnp1). It is not known how CENP-A(Cnp1) is specifically delivered to, and assembled into, centromeric chromatin. Through a screen for factors involved in kinetochore integrity in fission yeast, we identified Sim3. Sim...

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Main Authors: Dunleavy, Elaine M., Pidoux, Alison L., Monet, Marie, Bonilla, Carolina, Richardson, William, Hamilton, Georgina L., Ekwall, Karl, McLaughlin, Paul J., Allshire, Robin C.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193228/
https://ncbi.nlm.nih.gov/pubmed/18158900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.10.010
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