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Signal Transduction by Cxc Chemokine Receptor 4: Stromal Cell–Derived Factor 1 Stimulates Prolonged Protein Kinase B and Extracellular Signal–Regulated Kinase 2 Activation in T Lymphocytes
We report that stromal cell–derived factor (SDF)-1 has the remarkable capacity to induce sustained signaling through CXC chemokine receptor 4 (CXCR4). In contrast to other chemokines, such as monocyte chemotactic protein 1 (CC chemokine receptor 2 [CCR2]), macrophage inflammatory protein 1β (CCR5),...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193218/ https://ncbi.nlm.nih.gov/pubmed/10934220 |
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