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Coupling of Peripheral Tolerance to Endogenous Interleukin 10 Promotes Effective Modulation of Myelin-Activated T Cells and Ameliorates Experimental Allergic Encephalomyelitis

Several immune-based approaches are being considered for modulation of inflammatory T cells and amelioration of autoimmune diseases. The most recent strategies include simulation of peripheral self-tolerance by injection of adjuvant free antigen, local delivery of cytokines by genetically altered T...

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Detalhes bibliográficos
Main Authors: Legge, Kevin L., Min, Booki, Bell, J. Jeremiah, Caprio, Jacque C., Li, Lequn, Gregg, Randal K., Zaghouani, Habib
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193208/
https://ncbi.nlm.nih.gov/pubmed/10859329
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