Mitochondrial Basis for Immune Deficiency: Evidence from Purine Nucleoside Phosphorylase–Deficient Mice

We generated purine nucleoside phosphorylase (PNP)-deficient mice to gain insight into the mechanism of immune deficiency disease associated with PNP deficiency in humans. Similar to the human disease, PNP deficiency in mice causes an immunodeficiency that affects T lymphocytes more severely than B...

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Hlavní autoři: Arpaia, Enrico, Benveniste, Patricia, Di Cristofano, Antonio, Gu, Yiping, Dalal, Ilan, Kelly, Susan, Hershfield, Michael, Pandolfi, Pier Paolo, Roifman, Chaim M., Cohen, Amos
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2000
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193200/
https://ncbi.nlm.nih.gov/pubmed/10859343
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