Candidate Microbicides Block HIV-1 Infection of Human Immature Langerhans Cells within Epithelial Tissue Explants

Initial biologic events that underlie sexual transmission of HIV-1 are poorly understood. To model these events, we exposed human immature Langerhans cells (LCs) within epithelial tissue explants to two primary and two laboratory-adapted HIV-1 isolates. We detected HIV-1(Ba-L) infection in single LC...

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Detalhes bibliográficos
Main Authors: Kawamura, Tatsuyoshi, Cohen, Sandra S., Borris, Debra L., Aquilino, Elisabeth A., Glushakova, Svetlana, Margolis, Leonid B., Orenstein, Jan M., Offord, Robin E., Neurath, A. Robert, Blauvelt, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193188/
https://ncbi.nlm.nih.gov/pubmed/11085750
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