Role for Cathepsin F in Invariant Chain Processing and Major Histocompatibility Complex Class II Peptide Loading by Macrophages

The major histocompatibility complex (MHC) class II–associated invariant chain (Ii) regulates intracellular trafficking and peptide loading of MHC class II molecules. Such loading occurs after endosomal degradation of the invariant chain to a ∼3-kD peptide termed CLIP (class II–associated invariant...

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Main Authors: Shi, Guo-Ping, Bryant, Rebecca A.R., Riese, Richard, Verhelst, Steven, Driessen, Christoph, Li, Zhenqiang, Bromme, Dieter, Ploegh, Hidde L., Chapman, Harold A.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2000
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193169/
https://ncbi.nlm.nih.gov/pubmed/10748235
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