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Incomplete Cd8(+) T Lymphocyte Differentiation as a Mechanism for Subdominant Cytotoxic T Lymphocyte Responses to a Viral Antigen

CD8(+) cytotoxic T lymphocytes (CTLs) recognize antigen in the context of major histocompatibility complex (MHC) class I molecules. Class I epitopes have been classified as dominant or subdominant depending on the magnitude of the CTL response to the epitope. In this report, we have examined the in...

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Autori principali: Spencer, Juliet V., Braciale, Thomas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193146/
https://ncbi.nlm.nih.gov/pubmed/10811862
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