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The Formation of Immunogenic Major Histocompatibility Complex Class II–Peptide Ligands in Lysosomal Compartments of Dendritic Cells Is Regulated by Inflammatory Stimuli

During their final differentiation or maturation, dendritic cells (DCs) redistribute their major histocompatibility complex (MHC) class II products from intracellular compartments to the plasma membrane. Using cells arrested in the immature state, we now find that DCs also regulate the initial intra...

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Detalhes bibliográficos
Main Authors: Inaba, Kayo, Turley, Shannon, Iyoda, Tomonori, Yamaide, Fumiya, Shimoyama, Susumu, e Sousa, Caetano Reis, Germain, Ronald N., Mellman, Ira, Steinman, Ralph M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193115/
https://ncbi.nlm.nih.gov/pubmed/10727455
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