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Induction of Fas Ligand Expression by HIV Involves the Interaction of Nef with the T Cell Receptor ζ Chain

During HIV/SIV infection, there is widespread programmed cell death in infected and, perhaps more importantly, uninfected cells. Much of this apoptosis is mediated by Fas–Fas ligand (FasL) interactions. Previously we demonstrated in macaques that induction of FasL expression and apoptotic cell death...

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Detalhes bibliográficos
Main Authors: Xu, Xiao-Ning, Laffert, Bernd, Screaton, Gavin R., Kraft, Michael, Wolf, Dietlinde, Kolanus, Waldemar, Mongkolsapay, Juthathip, McMichael, Andrew J., Baur, Andreas S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193060/
https://ncbi.nlm.nih.gov/pubmed/10224289
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