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Identification of CD22 Ligands on Bone Marrow Sinusoidal Endothelium Implicated in CD22-dependent Homing of Recirculating B Cells

CD22 is a B cell–specific transmembrane protein known to function as a negative regulator of B cell signaling. It has also been implicated in cell adhesion through recognition of α2,6-linked sialic acids on glycans of target cells. Previous studies showed that CD22-deficient mice had a strongly redu...

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Autori principali: Nitschke, Lars, Floyd, Helen, Ferguson, David J.P., Crocker, Paul R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193059/
https://ncbi.nlm.nih.gov/pubmed/10224292
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