Lymphotoxin α/β and Tumor Necrosis Factor Are Required for Stromal Cell Expression of Homing Chemokines in B and T Cell Areas of the Spleen

Mice deficient in the cytokines tumor necrosis factor (TNF) or lymphotoxin (LT) α/β lack polarized B cell follicles in the spleen. Deficiency in CXC chemokine receptor 5 (CXCR5), a receptor for B lymphocyte chemoattractant (BLC), also causes loss of splenic follicles. Here we report that BLC express...

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Main Authors: Ngo, Vu N., Korner, Heinrich, Gunn, Michael D., Schmidt, Kerstin N., Sean Riminton, D., Cooper, Max D., Browning, Jeffrey L., Sedgwick, Jonathon D., Cyster, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192983/
https://ncbi.nlm.nih.gov/pubmed/9892622
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