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Cure of Progressive Murine Leishmaniasis: Interleukin 4 Dominance Is Abolished by Transient CD4(+) T Cell Depletion and T Helper Cell Type 1–selective Cytokine Therapy

Progressive infection with Leishmania major in susceptible BALB/c mice is mediated by interleukin (IL)-4–producing T helper cell type 2 (Th2) CD4(+) T cells that, once established, become resistant to Th1-deviating therapies with recombinant (r)IL-12 and/or neutralizing anti–IL-4 antibodies. We soug...

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書誌詳細
主要な著者: Heinzel, Frederick P., Rerko, Ronald M.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192969/
https://ncbi.nlm.nih.gov/pubmed/10377185
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