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TCR binding differs for a bacterial superantigen (SEE) and a viral superantigen (Mtv-9)

Both superantigens (SAG) and many anti-TCR monoclonal antibodies (mAb) have specificity for the V beta region of the TCR encoded by TCRBV genes. For instance the bacterial SAG staphylococcal enterotoxin E (SEE), the retroviral SAG MTV-9 and the mAb OT145 each react with human T cells expressing BV6S...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192839/
https://ncbi.nlm.nih.gov/pubmed/8879218
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